A double-blind comparative study of laser treatment with placebo laser (LED). The duration of hairloss and baldness, according to Hamilton classification, were recorded. A skin biopsy for histological examination was taken before and after treatment. In addition, a photograph was taken of the patients at the same time. Hair shaft thickness was measured with hair stretching equipment where the hairs can be stretched on a graded scale from 0-10. Normal value of hair shaft stretching is set at 5. All patients with the exception of one, in the laser treated group showed a complete stop of hair loss. All patients, except 3 showed a clear regrowth of hair with a reduction of at least one category in the Hamilton classification. The results were confirmed by histological examination. Pre-treatment typically showed the dermas with large, relatively normal amounts of follicles. Most of them were in the telogenphase and did not show any real hair. Some of the follicles were widened with keratin taps and follicle opening, post treatment showed the dermis with almost the same amount of hair follicles as pre-treatment, although a number of new follicles could be seen with clearly noticeable hair growth. 50% of the follicles are now in the anagenphase. A clearly visible regrowth of hairs were found in most treatment sample comparisons. When comparing the histological findings, transformation into more agnogenic hair follicles could be observed in 83% of the patients on laser treatment but in none of the placebo patients. Out of the 19 patients, 14 showed an increase in hair thickness, and all 18 showed improvement in general hair shaft quality measured with the hair stretcher. The results showed no improvement in the placebo group or any adverse effects of the treatment. The present double-blind study definitely showed that regrowth of new hairs can be achieved in most middle-aged and younger males with typical male baldness when the scalp is irradiated with Laser for 5 weeks, with follow up maintenance treatments. Material for the growth of the hair comes from the papilla. As long as the papilla is not destroyed, the hair will grow. If the hair is pulled out from the roots, it will nevertheless grow again. Should the papilla be destroyed, it will never grow again.
Wednesday, January 23, 2008
Hair loss, regrowth
A double-blind comparative study of laser treatment with placebo laser (LED). The duration of hairloss and baldness, according to Hamilton classification, were recorded. A skin biopsy for histological examination was taken before and after treatment. In addition, a photograph was taken of the patients at the same time. Hair shaft thickness was measured with hair stretching equipment where the hairs can be stretched on a graded scale from 0-10. Normal value of hair shaft stretching is set at 5. All patients with the exception of one, in the laser treated group showed a complete stop of hair loss. All patients, except 3 showed a clear regrowth of hair with a reduction of at least one category in the Hamilton classification. The results were confirmed by histological examination. Pre-treatment typically showed the dermas with large, relatively normal amounts of follicles. Most of them were in the telogenphase and did not show any real hair. Some of the follicles were widened with keratin taps and follicle opening, post treatment showed the dermis with almost the same amount of hair follicles as pre-treatment, although a number of new follicles could be seen with clearly noticeable hair growth. 50% of the follicles are now in the anagenphase. A clearly visible regrowth of hairs were found in most treatment sample comparisons. When comparing the histological findings, transformation into more agnogenic hair follicles could be observed in 83% of the patients on laser treatment but in none of the placebo patients. Out of the 19 patients, 14 showed an increase in hair thickness, and all 18 showed improvement in general hair shaft quality measured with the hair stretcher. The results showed no improvement in the placebo group or any adverse effects of the treatment. The present double-blind study definitely showed that regrowth of new hairs can be achieved in most middle-aged and younger males with typical male baldness when the scalp is irradiated with Laser for 5 weeks, with follow up maintenance treatments. Material for the growth of the hair comes from the papilla. As long as the papilla is not destroyed, the hair will grow. If the hair is pulled out from the roots, it will nevertheless grow again. Should the papilla be destroyed, it will never grow again.
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